Marloes Henckens

STRESS LAB 

The research of our lab aims at understanding how stress exposure can lastingly affect brain function. Using animal models that allow for controlled study of the mechanistic underpinnings of stress-related psychopathology, we aim to elucidate how stress affects brain function at the molecular (investigating epigenetic mechanisms and local gene expression) and neural circuit level (by means of neuronal activation markers, rodent MRI, viral tracing and optogenetics), while warranting translational value. Particular focus is put on the inter-individual differences in the neural correlates of stress responsivity and subsequent coping, as the natural resiliency against developing stress-related mental disorders likely contains unique information for new treatment options for those suffering from disease.